American Cruise Lines

Upper Mississippi (St. Louis to St. Paul)

Upper Mississippi (St. Louis to St. Paul), 8-night on American Serenade by American Cruise Lines. Departs July 10, 2026 from Saint Louis, Missouri to Saint Paul, Minnesota. Itinerary includes Saint Louis, Missouri, Alton, Illinois,...

Cruise summary

Cruise line
American Cruise Lines
Ship
American Serenade
Departure
July 10, 2026
Duration
8-night
Embarkation
Saint Louis, Missouri
Disembarkation
Saint Paul, Minnesota

Itinerary highlights

  1. Saint Louis, Missouri
  2. Alton, Illinois
  3. Hannibal, Missouri
  4. Muscatine, Iowa
  5. Dubuque, Iowa
  6. Winona, Minnesota